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Rabbit Anti-beta-Actin (Loading Control) antibody (bs-0061R)
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產品編號 bs-0061R
英文名稱 beta-Actin (Loading Control)
中文名稱 β-肌動蛋白/β-Actin(內參)抗體
別    名 Beta Actin; beta-Actin; ACTB; Actin cytoplasmic 1; Actin, beta; Beta actin; beta cytoskeletal actin;A X actin like protein; ACTB; Actin cytoplasmic 1; alpha sarcomeric Actin; Actx; Beta cytoskeletal actin; Melanoma X actin; PS1TP5BP1; ACTB_HUMAN.  
Specific References  (445)     |     bs-0061R has been referenced in 445 publications.
[IF=11.48] Lan, Feng, et al. "Forkhead box protein 3 in human nasal polyp regulatory T cells is regulated by the protein suppressor of cytokine signaling 3." Journal of Allergy and Clinical Immunology 132.6 (2013): 1314-1321.  WB ;  Human.  
[IF=11.33] Leclercq, Sophie, et al. "Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior." Nature Communications 8 (2017): 15062.  WB ;  Mouse.  
[IF=9.13] Yoshino et al. PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2α-Targeting Therapy for Renal Cell Carcinoma. (2017) Cancer.Res. 77:6321-6329  WB ;  human.  
[IF=8.032] Matsui H et al. Age- and α-Synuclein-Dependent Degeneration of Dopamine and Noradrenaline Neurons in the Annual Killifish Nothobranchius furzeri. Cell Rep. 2019 Feb 12;26(7):1727-1733.e6.  WB ;  Fish.  
[IF=7.82] Han, Jianfeng, et al. "Cationic Bovine Serum Albumin Based Self‐Assembled Nanoparticles as siRNA Delivery Vector for Treating Lung Metastatic Cancer." Small 10.3 (2014): 524-535.  WB ;  Mouse.  
[IF=7.6] Teng, I., et al. "Phospholipid-functionalized mesoporous silica nanocarriers for selective photodynamic therapy of cancer." Biomaterials (2013).  WB ;  Mouse.  
[IF=7.6] Xiang, Bai, et al. "PSA-responsive and PSMA-mediated multifunctional liposomes for targeted therapy of prostate cancer." Biomaterials (2013).  WB ;  Human.  
[IF=6.941] Yang P et al. Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway. (2018) Cancer Letters. Dec 1;438:76-85.  WB ;  Mouse.  
[IF=6.41] Long, Yan-Min, et al. "Negatively charged silver nanoparticles cause retinal vascular permeability by activating plasma contact system and disrupting adherens junction." Nanotoxicology (2015): 1-11.  WB ;  
[IF=6.36] Yoshino, Hirofumi, et al. "microRNA-210-3p depletion by CRISPR/Cas9 promoted tumorigenesis through revival of TWIST1 in renal cell carcinoma." Oncotarget.   WB ;  Human.  
[IF=6.34] Li, Xiaoxia, et al. "AMP-activated protein kinase promotes the differentiation of endothelial progenitor cells." Arteriosclerosis, thrombosis, and vascular biology 28.10 (2008): 1789-1795.  WB ;  Human.  
[IF=6.217] Wang L et al. Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle arrest through the Erk1/2 and Akt pathways. J Exp Clin?Cancer?Res.?2019 Feb 21;38(1):93.  WB ;  Human.  
[IF=6.02] Zhang J et al. Disruption of the Superoxide Anions-Mitophagy Regulation Axis Mediates Copper Oxide Nanoparticles-Induced Vascular Endothelial Cell Death. Free Radic. Biol. Med. Sep 21;129:268-278  WB ;  Human.  
[IF=6.02] Bodas M et al. Autophagy augmentation alleviates cigarette smoke-induced CFTR-dysfunction, ceramide-accumulation and COPD-emphysema pathogenesis.(2018) Free Radic Biol Med.131:81-97.   WB ;  Human.  
[IF=5.922] Sakaguchi et al. Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer. (2017) Br.J.Cancer. 116:1077-1087  WB ;  Human.  
[IF=5.595] Liu T et al. MicroRNA-493 targets STMN-1 and promotes hypoxia-induced epithelial cell cycle arrest in G/M and renal fibrosis. (2018) FASEB J. Sep 05  WB ;  Mouse.  
[IF=5.595] Li J et al. Ceria?nanoparticles?enhance?endochondral?ossification-based?critical-sized?bone?defectregeneration?by?promoting?the?hypertrophic?differentiation?of?BMSCs?via?DHX15 activation. FASEB J. 2019 Feb 18:fj201802187R.  WB ;  Mouse.  
[IF=5.58] Cai, Xingcai, et al. "Alpha-ketoglutarate promotes skeletal muscle hypertrophy and protein synthesis through Akt/mTOR signaling pathways."Scientific Reports 6 (2016): 26802.  WB ;  Mouse.  
[IF=5.58]  Zhou, Xiaoqiao, et al. "Cecropin B Represses CYP3A29 Expression through Activation of the TLR2/4-NF-κB/PXR Signaling Pathway." Scientific Reports6 (2016): 27876.  WB ;  Pig.  
[IF=5.57] Sakaguchi, Takashi, et al. "Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer." British journal of cancer 116.8 (2017): 1077.  WB ;  Human.  
[IF=5.54] Yoshihara et al. Lactosylceramide synthases encoded by B4galt5 and 6 genes are pivotal for neuronal generation and myelin formation in mice. (2018) PLoS.Genet. 14:e1007545  WB ;  Mouse.  
[IF=5.511] Voogdt et al. Evolutionary Regression and Species-Specific Codon Usage of TLR15. (2018) Front.Immunol. 9:2626  WB ;  Human.  
[IF=5.5] Cai, Xingcai, et al. "α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway." The FASEB Journal (2017): fj-201700670R.  WB ;  
[IF=5.5] Zhang et al. Cardiac Contractility Modulation Attenuate Myocardial Fibrosis by Inhibiting TGF-β1/Smad3 Signaling Pathway in a Rabbit Model of Chronic Heart Failure. (2016) Cell.Physiol.Biochem. 39:294-307  WB ;  Rabbit.  
[IF=5.5] Deng G et al. miR-136-5p Regulates the Inflammatory Response by Targeting the IKKβ/NF-κB/A20 Pathway After Spinal Cord Injury.(2018) Cell Physiol Biochem;50:512-524   WB ;  Rat .  
[IF=5.48] Wu, Bin, et al. "Succinate-induced neuronal mitochondrial fission and hexokinase II malfunction in ischemic stroke: Therapeutical effects of kaempferol." Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease (2017).  WB ;  Mouse.  
[IF=5.41] Yan, Wenjun, et al. "SirT1 mediates hyperbaric oxygen preconditioning-induced ischemic tolerance in rat brain." Journal of Cerebral Blood Flow & Metabolism 33.3 (2013): 396-406.  Rat.  
[IF=5.253] Liu,et al.Slit2/Robo1 signaling is involved in angiogenesis of glomerular endothelial cells exposed to a diabetic-like environment.(2018) Angiogenesis. 21:237-249.  WB ;  Human.  
[IF=5.23] Zhuang, Pengwei, et al. "cAMP-PKA-CaMKII signaling pathway is involved in aggravated cardiotoxicity during Fuzi and Beimu Combination Treatment of Experimental Pulmonary Hypertension." Scientific Reports 6 (2016): 34903.  WB ;  Rat.  
[IF=5.21] Ma, Yanqin, et al. "Inflammatory responses induced by fluoride and arsenic at toxic concentration in rabbit aorta." Archives of toxicology 86.6 (2012): 849-856.  WB ;  Rabbit.  
[IF=5.17] Xu et al. Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression. (2015) Oncotarge. 6:26161-76  WB ;  Human.  
[IF=5.17] Sun et al. YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo. (2016) Oncotarge. 7:81062-81076  WB ;  Human.  
[IF=5.17] Li et al. Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma. (2015) Oncotarge. 6:1544-55  WB ;  Human.  
[IF=5.17] Xu et al. Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression. (2015) Oncotarge. 6:26161-76  WB ;  Human.  
[IF=5.17] Sun et al. YAP1 enhances cell proliferation, migration, and invasion of gastric cancer in vitro and in vivo. (2016) Oncotarge. 7:81062-81076  WB ;  Human.  
[IF=5.168] Wang,et al.Time-dependent effects of late-onset dietary intake of salidroside on lifespan and age-related biomarkers of the annual fish Nothobranchius guentheri.(2018) Oncotarget. 9:14882-14894.  WB ;  Fish.  
[IF=5.14] Xu, Xiaofeng, et al. "Preferential Heme Oxygenase-1 Activation in Striatal Astrocytes Antagonizes Dopaminergic Neuron Degeneration in MPTP-Intoxicated Mice." Molecular Neurobiology (2015): 1-10.  WB ;  Mouse.  
[IF=5.14] Xu, Xiaofeng, et al. "Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan."Molecular Neurobiology (2016): 1-9.  WB ;  
[IF=5.13] Liu, Qun, et al. "6-Shogaol induces apoptosis in human leukemia cells through a process involving caspase-mediated cleavage of eIF2α." Molecular cancer 12.1 (2013): 135.  WB ;  Human.  
[IF=5.1] Ling, Feng, et al. "Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300." Oncotarget 8.42 (2017): 72773.  WB ;  
[IF=5.07] Song, Dongmei, et al. "Ulinastatin Activates Heme Oxygenase‐1 Antioxidant Pathway and Attenuates Allergic Inflammation." British Journal of Pharmacology (2014).  WB ;  Mouse.  
[IF=5] Tamburrino et al. The CatSper calcium channel in human sperm: relation with motility and involvement in progesterone-induced acrosome reaction. (2014) Hum.Reprod. 29:418-28  other ;  Human.  
[IF=5] Li, Bo, et al. "Long noncoding RNA CCAT1 functions as a ceRNA to antagonize the effect of miR-410 on the down-regulation of ITPKB in human HCT-116 and HCT-8 cells." Oncotarget 8.54 (2017): 92855.  WB ;  Human.  
[IF=4.87] Liu H et al. Lactoferrin protects against iron dysregulation, oxidative stress, and apoptosis in MPTP‐induced Parkinson's disease in mice. J Neurochem. 2019 Aug 23.   WB ;  Mouse.  
[IF=4.784] Wan B et al. Porcine FcγRIIb mediated PRRSV ADE infection through inhibiting IFN-β by cytoplasmic inhibitory signal transduction. Int J Biol Macromol. 2019 Jul 5;138:198-206.   WB ;  Monkey.  
[IF=4.653] Wang C et al. Human Milk Oligosaccharides Protect Against Necrotizing Enterocolitis by Inhibiting Intestinal Damage Via Increasing the Proliferation of Crypt Cells. Mol Nutr Food Res. 2019 Jun 17:e1900262.   WB ;  Mouse.  
[IF=4.652] Yang et al. SIRT1 regulates CD40 expression induced by TNF-α via NF-?B pathway in endothelial cells. (2012) Cell.Physiol.Bioche. 30:1287-98  WB ;  Human.  
[IF=4.609] Shen et al. Cortical spreading depression preconditioning mediates neuroprotection against ischemic stroke by inducing AMP-activated protein kinase-dependent autophagy in a rat cerebral ischemic/reperfusion injury model. (2017) J.Neurochem. 140:799-813  WB ;  Rat.  
[IF=4.57] Tsuboi, Koichiro, et al. "Autophagy protects against colitis by the maintenance of normal gut microflora and secretion of mucus." Journal of Biological Chemistry 290.33 (2015): 20511-20526.  WB ;  Mouse.  
[IF=4.56] Xia et al. Mettl3 Mutation Disrupts Gamete Maturation and Reduces Fertility in Zebrafish. (2017) Genetics.   WB ;  Zebrafish.  
[IF=4.56] Wu et al. Calcineurin B stimulates cytokine production through a CD14-independent Toll-like receptor 4 pathway. (2016) Immunol.Cell.Bio. 94:285-92  WB ;  Human.  
[IF=4.53] Zheng D et al. Long noncoding RNA Crnde attenuates cardiac fibrosis via Smad3-Crnde negative feedback in diabetic cardiomyopathy. FEBS J. 2019 Feb 12.   WB ;  Mouse.  
[IF=4.5] Jiao, Zhang Jiao, et al. "MicroRNA-1285 regulates 17β-estradiol-inhibited immature boar Sertoli cell proliferation via adenosine monophosphate-activated protein kinase activation." Endocrinology (2015): en-2014.  WB ;  
[IF=4.473] Wu et al. Calcineurin B stimulates cytokine production through a CD14-independent Toll-like receptor 4 pathway. (2016) Immunol.Cell.Bio. 94:285-92  WB ;  Human.  
[IF=4.41] Zeng, Xiaoyun, et al. "A Newly Synthesized Sinapic Acid Derivative Inhibits Endothelial Activation In Vitro and In Vivo." Molecular Pharmacology (2013).  WB ;  Human.  
[IF=4.38] Zhu, Yuxuan, et al. "Antioxidant and Antiapoptotic Effects of 1, 1′-(Biphenyl-4, 4′-diyl)-bis (3-(dimethylamino)-propan-1-one) on Protecting PC12 Cells from Aβ-Induced Injury." Molecular pharmaceutics 11.2 (2013): 428-435.  WB ;  Rat.  
[IF=4.379] Pan et al. Anti-Obesity Effect of Chitosan Oligosaccharide Capsules (COSCs) in Obese Rats by Ameliorating Leptin Resistance and Adipogenesis. (2018) Mar.Drugs. 16   WB  ;  Rabbit.  
[IF=4.302] Song JL et al. Functional role of RRS 1 in breast cancer cell proliferation.(2018) J Cell Mol Med. Dec;22(12):6304-6313.   WB ;  Human.  
[IF=4.302] Zuo L et al. PI3-kinase/Akt?pathway-regulated?membrane?transportation?of?acid-sensing?ion?channel1a/Calcium?ion?influx/endoplasmic?reticulum?stress?activation?on?PDGF-induced HSC?Activation. J Cell Mol Med. 2019 Apr 2.   WB ;  Rat.  
[IF=4.263] Wu X et al.The role of Ca 2+ in acid-sensing ion channel 1a-mediated chondrocyte pyroptosis in rat adjuvant arthritis.(2018) Lab Invest.   WB ;  Rat .  
[IF=4.26] Wang, Ye-Jun, et al. "Two oral HBx vaccines delivered by live attenuated< i> Salmonella: Both eliciting effective anti-tumor immunity." Cancer letters 263.1 (2008): 67-76.  WB ;  
[IF=4.26] Li, Chengcheng, et al. "Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway." Scientific Reports 7 (2017).  WB ;  Mouse.  
[IF=4.258] Yang et al. RPB5-mediating protein is required for the proliferation of hepatocellular carcinoma cells. (2011) J.Biol.Che. 286:11865-74  WB ;  Human.  
[IF=4.22] Hou, Yiling, et al. "Structure elucidation, proliferation effect on macrophage and its mechanism of a new heteropolysaccharide from Lactarius deliciosus Gray." Carbohydrate Polymers (2016).  WB ;  Other Species.  
[IF=4.2] Yang, Wucai, et al. "Melatonin promotes triacylglycerol accumulation via MT2 receptor during differentiation in bovine intramuscular preadipocytes." Scientific Reports 7.1 (2017): 15080.  WB ;  Bovine.  
[IF=4.181] Ogura et al. Vibrio cholerae Cholix Toxin-Induced HepG2 Cell Death is Enhanced by Tumor Necrosis Factor-Alpha Through ROS and Intracellular Signal-Regulated Kinases. (2017) Toxicol.Sci. 156:455-468  WB ;  Mouse.  
[IF=4.13] Fu, Chenglai, et al. "Cholesterol increases adhesion of monocytes to endothelium by moving adhesion molecules out of caveolae." Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids 1801.7 (2010): 702-710.  WB ;  
[IF=4.122] Zhang et al. Non-thermal plasma treatment improves chicken sperm motility via the regulation of demethylation levels. (2018) Sci.Rep. 8:7576  WB ;  Chicken.  
[IF=4.12] Wang et al. Kukoamine A inhibits human glioblastoma cell growth and migration through apoptosis induction and epithelial-mesenchymal transition attenuation. (2016) Sci.Rep. 6:36543  WB ;  Human.  
[IF=4.021] Dinesh P et al. Berberine mitigates IL-21/IL-21R mediated autophagic influx in fibroblast-like synoviocytes and regulates Th17/Treg imbalance in rheumatoid arthritis. Apoptosis.?2019 May 20.?  WB ;  Rat.  
[IF=3.994] Wang Z et al. Effects of exercise-induced fatigue on the morphology of asymmetric synapse and synaptic protein levels in rat striatum. Neurochem Int. 2019 May 27;129:104476.  WB ;  Rat.  
[IF=3.98] Lu, Naisheng, et al. "Butyric acid regulates progesterone and estradiol secretion via cAMP signaling pathway in porcine granulosa cells." The Journal of Steroid Biochemistry and Molecular Biology (2017).  WB ;  Pig.  
[IF=3.974] Li S et al. Detection of Aflatoxin adducts as potential markers and the role of curcumin in alleviating AFB1-induced liver damage in chickens.Ecotoxicol Environ Saf. 2019 Jul 30;176:137-145.   WB ;  Chicken.  
[IF=3.923] Song LL et al. TGF-β and HSP70 profiles during transformation of yak hair follicles from the anagen to catagen stage. J Cell Physiol. 2019 Feb 5.   WB ;  Yak.  
[IF=3.92] Du, Si‐Qi, et al. "Acupuncture inhibits TXNIP‐associated oxidative stress and inflammation to attenuate cognitive impairment in vascular dementia rats." CNS Neuroscience & Therapeutics (2017).  WB ;  Rat.  
[IF=3.88] Ogura, Kohei, et al. "Vibrio cholerae Cholix toxin-induced HepG2 cell death is enhanced by tumor necrosis factor-alpha through ROS and intracellular signal-regulated kinases." Toxicological Sciences (2017): kfx009.  WB ;  Mouse.  
[IF=3.87] Hou, Yiling, et al. "Structure elucidation and antitumor activity of a new polysaccharide from Maerkang Tricholoma matsutake." International Journal of Biological Sciences 13.7 (2017): 935-948.  WB ;  Mouse.  
[IF=3.86] Ommati, Mohammad Mehdi, et al. "Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models." Toxicology letters (2017).  WB ;  Rat.  
[IF=3.85] Wu, Yuting, et al. "Methylation of Septin9 mediated by DNMT3a enhances hepatic stellate cells activation and liver fibrogenesis." Toxicology and Applied Pharmacology 315 (2017): 35-49.  WB ;  Mouse.  
[IF=3.85] Li, Yue, et al. "Autophagy contributes to 4-Amino-2-Trifluoromethyl-Phenyl Retinate-induced differentiation in human acute promyelocytic leukemia NB4 cells." Toxicology and Applied Pharmacology. (2017).  Human.  
[IF=3.85] Huang, Huimin, et al. "HMGA2, a driver of inflammation, is associated with hypermethylation in acute liver injury." Toxicology and Applied Pharmacology (2017).  WB ;  Mouse.  
[IF=3.84] Yin, Di, et al. "Functional graphene oxide as a plasmid-based Stat3 siRNA carrier inhibits mouse malignant melanoma growth in vivo." Nanotechnology 24.10 (2013): 105102.  WB ;  Mouse.  
[IF=3.84] Yin, Di, et al. "Functional graphene oxide as a plasmid-based Stat3 siRNA carrier inhibits mouse malignant melanoma growth in vivo." Nanotechnology 24.10 (2013): 105102.  WB ;  
[IF=3.84] Chen, Siying, et al. "HDACI regulates the PI3K/Akt signaling pathway to reverse MCF-7/PTX resistance by inhibiting SET." RSC Advances (2016).  WB ;  Human.  
[IF=3.84] Shen, P. P., et al. "Cortical Spreading Depression (CSD) Preconditioning Mediates Neuroprotection against Ischemic Stroke by Inducing AMP‐activated Protein Kinase‐dependent Autophagy in a Rat Cerebral Ischemic/reperfusion Injury Model." Journal of Neurochemistry (2016).  WB ;  Rat.  
[IF=3.83] Cheng et al. miR-203 Inhibits Alcohol-Induced Hepatic Steatosis by Targeting Lipin1. (2018) Front.Pharmacol. 9:275  WB ;  Mouse.  
[IF=3.817] Zhao et al. Involvement of DNA polymerase β overexpression in the malignant transformation induced by benzo[a]pyrene. (2013) Toxicolog. 309:73-80  WB ;  Mouse.  
[IF=3.81] Huang, Yu‐lin, et al. "Spermatogenesis‐associated proteins at different developmental stages of buffalo testicular seminiferous tubules identified by comparative proteomic analysis." Proteomics (2016).  WB ;  Other Species.  
[IF=3.79] Wang, Xiaoqiu, et al. "Temporal Proteomic Analysis Reveals Defects in Small Intestinal Development of Porcine Fetuses with Intrauterine Growth Restriction." The Journal of Nutritional Biochemistry (2014).  WB ;  
[IF=3.79] Fu, Yujie, et al. "Activity of the anti-estrogenic cajanin stilbene acid towards breast cancer." The Journal of Nutritional Biochemistry (2015).  WB ;  Human.  
[IF=3.786] Shen XF et al. Role of DNA hypomethylation in lateral habenular nucleus is involved in the development of depressive-like behavior in rats.J Affect Disord. 2019 Jun 1;252:373-381.  WB ;  Rat.  
[IF=3.77] Miao, Xue-Rong, et al. "[EXPRESS] DNMT3a contributes to the development and maintenance of bone cancer pain by silencing Kv1. 2 expression in spinal cord dorsal horn." Molecular Pain 13 (2017): 1744806917740681.  WB ;  Rat.  
[IF=3.766] Song G et al. Chrysophanol attenuates airway inflammation and remodeling through nuclear factor‐kappa B signaling pathway in asthma. Phytother Res. 2019 Jul 17.   WB ;  Mouse&Human.  
[IF=3.743] Lu Y et al. Baicalin regulates depression behavior in mice exposed to chronic mild stress via the Rac/LIMK/cofilin pathway. Biomed Pharmacother. 2019 Aug;116:109054.  WB ;  Mouse.  
[IF=3.74] Yuan, Zuoqing, et al. "Changes on lipid peroxidation, enzymatic activities and gene expression in planarian (Dugesia japonica) following exposure to perfluorooctanoic acid." Ecotoxicology and Environmental Safety 145 (2017): 564-568.  WB ;  Other Species.  
[IF=3.73] Wang, Wei, et al. "Cynoglossus semilaevis ISG15: A Secreted Cytokine-Like Protein That Stimulates Antiviral Immune Response in a LRGG Motif-Dependent Manner." PLOS ONE 7.9 (2012): e44884.  WB ;  
[IF=3.73] Gao, Jin-Hang, et al. "Celecoxib Ameliorates Portal Hypertension of the Cirrhotic Rats through the Dual Inhibitory Effects on the Intrahepatic Fibrosis and Angiogenesis." PLOS ONE 8.7 (2013): e69309.  WB ;  Rat.  
[IF=3.73] Hou, Cong-Cong, and Wan-Xi Yang. "Acroframosome-Dependent KIFC1 Facilitates Acrosome Formation during Spermatogenesis in the Caridean Shrimp Exopalaemon modestus."?PLOS ONE?8.9 (2013): e76065.  WB ;  
[IF=3.7] Wu, Yuting, et al. "Silent information regulator 1 (SIRT1) ameliorates liver fibrosis via promoting activated stellate cell apoptosis and reversion."Toxicology and Applied Pharmacology (2015).  WB ;  Mouse.  
[IF=3.7] Ma, Yanqin, et al. "Arsenic and fluoride induce apoptosis, inflammation and oxidative stress in cultured human umbilical vein endothelial cells." Chemosphere 167 (2017): 454-461.  WB ;  Human.  
[IF=3.687] Pang et al. Inhibitory Effect of Methotrexate on Rheumatoid Arthritis Inflammation and Comprehensive Metabolomics Analysis Using Ultra-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry (UPLC-Q/TOF-MS). (2018) Int.J.Mol.Sci. 19   WB ;  Rat.  
[IF=3.68] Wang et al. Abortive infection of snakehead fish vesiculovirus in ZF4 cells was associated with the RLRs pathway activation by viral replicative intermediates. (2015) Int.J.Mol.Sci. 16:6235-50  Control,WB ;  Zebrafish.  
[IF=3.68] Li et al. Berberine Alleviates Olanzapine-Induced Adipogenesis via the AMPKα-SREBP Pathway in 3T3-L1 Cells. (2016) Int.J.Mol.Sci. 17   WB ;  Mouse.  
[IF=3.68] He, Mu-Dan, et al. "Efficient ligase 3-dependent microhomology-mediated end joining repair of DNA double-strand breaks in zebrafish embryos." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis (2015).  WB ;  
[IF=3.68] Zhong et al. High-temperature cultivation of recombinant Pichia pastoris increases endoplasmic reticulum stress and decreases production of human interleukin-10. (2014) Microb.Cell.Fac. 13:163  WB ;  
[IF=3.64] Shi, Ran-ran, et al. "The immunogenicity of a novel cytotoxic T lymphocyte epitope from tumor antigen PL2L60 could be enhanced by 4-chlorophenylalanine substitution at position 1."?Cancer Immunology, Immunotherapy?(2013): 1-10.  WB ;  Human.  
[IF=3.62] Wang, Peng, et al. "Trans-generational enhancement of C-type lysozyme level in eggs of zebrafish by dietary β-glucan." Developmental & Comparative Immunology (2017).  other ;  
[IF=3.616] Sun X et al. Methamphetamine produces cardiac damage and apoptosis by decreasing melusin.Toxicol Appl Pharmacol. 2019 Mar 20.   WB ;  Rat.  
[IF=3.61] Wang, Li, et al. "Silencing stem cell factor attenuates stemness and inhibits migration of cancer stem cells derived from Lewis lung carcinoma cells."Tumor Biology (2015): 1-15.  WB ;  Mouse.  
[IF=3.609] Yan et al. Effects of mitochondrial translocation of telomerase on drug resistance in hepatocellular carcinoma cells. (2015) J.Cance. 6:151-9  WB ;  Human.  
[IF=3.585] Feng Y et al. ATPR-induced differentiation and G0/G1 phase arrest in acute promyelocytic leukemia by repressing EBP50/NCF1 complex to promote the production of ROS. Toxicol Appl Pharmacol. 2019 Jun 27;379:114638.  WB ;  Mouse&Human.  
[IF=3.571] Tian M et al. Dietary Branched-Chain Amino Acids Regulate Food Intake Partly through Intestinal and Hypothalamic Amino Acid Receptors in Piglets. J Agric Food Chem. 2019 Jun 19;67(24):6809-6818.   WB ;  Piglet.  
[IF=3.571] Huang H et al. AMPK mediates the neurotoxicity of iron oxide nanoparticles retained in mitochondria or lysosomes. Metallomics. 2019 Jun 26.  WB ;  Human.  
[IF=3.562] Liu YJ et al. The expression of three opsin genes and phototactic behavior of Spodoptera exigua (Lepidoptera: Noctuidae): evidence for visual function of opsin in phototaxis.Insect Biochem Mol Biol. 2018 May;96:27-35.  WB ;  Moth.  
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[IF=2.62] Li, Zhifu, et al. "Celecoxib Combined with Diacerein Effectively Alleviates Osteoarthritis in Rats via Regulating JNK and p38MAPK Signaling Pathways." Inflammation 38.4 (2015): 1563-1572.  WB ;  Rat.  
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[IF=2.589] Xiao L et al. Profile?of?melatonin?and its?receptors?and?synthesizing?enzymes?in?cumulus-oocyte?complexes?of the?developing?sheep?antral?follicle-a?potential?estradiol-mediated?mechanism. Reprod Biol Endocrinol. 2019 Jan 3;17(1):1.  WB ;  Sheep.  
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[IF=2.58] Huang, Xu, et al. "ICAM-1-Targeted Liposomes Loaded with Liver X Receptor Agonists Suppress PDGF-Induced Proliferation of Vascular Smooth Muscle Cells." Nanoscale Research Letters 12.1 (2017): 322.  WB ;  Mouse.  
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[IF=2.575] Tan LL et al. Inhibition of microRNA-17-5p reduces the inflammation and lipid accumulation, and up-regulates ATP-binding cassette transporterA1 in atherosclerosis. Journal of Pharmacological Sciences.2018.  WB ;  Mouse.  
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[IF=2.072] Wang J et al. Oral supplementation with ginseng polysaccharide promotes food intake in mice. Brain Behav. 2019 Aug 8:e01340.   WB ;  Mouse.  
[IF=2.064] Yao Q et al.Lycium Barbarum Polysaccharides Improve Retinopathy in Diabetic Sprague-Dawley Rats.(2018)Evid Based Complement Alternat Med.Nov 15;2018:7943212.   WB ;  Rat.  
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[IF=1.93] Xiong, Zhang, et al. "Curcumin mediates presenilin-1 activity to reduce β-amyloid production in a model of Alzheimer’s Disease." Pharmacological Reports 63.5 (2011): 1101-1108.  WB ;  Human.  
[IF=1.922] Bai et al. miR?29a?3p represses proliferation and metastasis of gastric cancer cells via attenuating HAS3 levels. (2018) Mol.Med.Rep. 17:8145-8152  WB ;  human.  
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[IF=1.922] Zhu Y et al. MicroRNA?34a mediates atrial fibrillation through regulation of Ankyrin?B expression.Mol Med Rep. 2018 Jun;17(6):8457-8465.  WB ;  Human.  
[IF=1.922] Liu Z et al. N-terminal truncated peroxisome proliferator?activated receptor?γ coactivator?1α alleviates phenylephrine?induced mitochondrial dysfunction and decreases lipid droplet accumulation in neonatal rat cardiomyocytes. Mol Med Rep. 2018 Aug;18(2):2142-2152.  WB ;  Rat.  
[IF=1.92] Yu et al. Inhibition of autophagy enhanced cobalt chloride?induced apoptosis in rat alveolar type?II epithelial cells. (2018) Mol.Med.Rep. 18:2124-2132  WB ;  Rat.  
[IF=1.92] Liu, Chen, et al. "Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system." BMC Cardiovascular Disorders 16.1 (2016): 192.  WB ;  Dog.  
[IF=1.894] Zhang T et al. Resveratrol Reduces Oxidative Stress and Apoptosis in Podocytes via Sir2-Related Enzymes, Sirtuins1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Co-Activator 1α (PGC-1α) Axis. Med Sci Monit. 2019 Feb 15;25:1220-1231.   WB ;  Mouse.  
[IF=1.892] Li CL et al. Preparation and In Vivo Expression of CS-PEI/pCGRP Complex for Promoting Fracture Healing. International Journal of Polymer Science.2019 9432194.  WB ;  Rat.  
[IF=1.89] Zong, Shaohui, et al. "Effects of Polygonatum sibiricum polysaccharide on the osteogenic differentiation of bone mesenchymal stem cells in mice." International Journal of Clinical and Experimental Pathology8.6 (2015): 6169-6180.  WB ;  Mouse.  
[IF=1.871] Huang XW et al. Scutellarein suppresses Aβ?induced memory impairment via inhibition of the NF?κB pathway in vivo and in vitro. Oncol Lett. 2019 Jun;17(6):5581-5589.  WB ;  Rat.  
[IF=1.871] Meng H et al. NEDD9 promotes invasion and migration of colorectal cancer cell line HCT116 via JNK/EMT. ONCOLOGY LETTERS.2019 18: 4022-4029.  WB ;  Human.  
[IF=1.87] Xin, Ruijuan, et al. "MicroRNA-214 promotes peritoneal metastasis through regulating PTEN negatively in gastric cancer." Clinics and Research in Hepatology and Gastroenterology (2016).  WB ;  Human.  
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[IF=1.84] Yao, Xiaolei, et al. "Characterization of GALNTL5 gene sequence and expression in ovine testes and sperm." Theriogenology (2017).  WB ;  Sheep.  
[IF=1.83] Li, Gongchu, et al. "Ulva pertusa lectin 1 delivery through adenovirus vector affects multiple signaling pathways in cancer cells." Glycoconjugate Journal (2017): 1-10.  WB ;  Human.  
[IF=1.8] Zhao, Yangfei, et al. "Effect of Choline on the Composition and Degradation Enzyme of Extracellular Matrix of Mice Chondrocytes Exposed to Fluoride."Biological Trace Element Research (2016): 1-7.  WB ;  Mouse.  
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[IF=1.654] Yao C et al. Data Mining and Validation of AMPK Pathway as a Novel Candidate Role Affecting Intramuscular Fat Content in Pigs. Animals (Basel). 2019 Apr 1;9(4). pii: E137.   WB ;  Pig.  
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[IF=1.607] Zhao B et al. N‐Acetyl‐d‐galactosamine prevents soya bean agglutinin‐induced intestinal barrier dysfunction in intestinal porcine epithelial cells. J Anim Physiol Anim Nutr (Berl). 2019 Apr 1.  WB ;  Porcine.  
[IF=1.58] Zhang et al. Protective effect of heme oxygenase-1 on Wistar rats with heart failure through the inhibition of inflammation and amelioration of intestinal microcirculation. (2015) J.Geriatr.Cardiol. 12:353-65  WB ;  Rat.  
[IF=1.58] Lu, Wei, et al. "MicroRNA-421 enhances cell migration and invasion by down-regulating TIMP-2 in glioblastoma." Int J Clin Exp Med 9.8 (2016): 15876-15883.  WB ;  Human.  
[IF=1.56] Xiang, Yan, et al. "Effect of Yi Guan Jian decoction on differentiation of bone marrow mesenchymalstem cells into hepatocyte-like cells in dimethylnitrosamine-induced liver cirrhosis in mice." Molecular Medicine Reports.  WB ;  Mouse.  
[IF=1.56] Du, Jinghua, et al. "TLR4?dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." Molecular medicine reports 13.3 (2016): 2159-2166.  WB ;  Mouse.  
[IF=1.559] Li et al. Lipopolysaccharide induces inflammation and facilitates lung metastasis in a breast cancer model via the prostaglandin?E2-EP2 pathway. (2015) Mol.Med.Re. 11:4454-62  WB ;  Mouse.  
[IF=1.55] Chang, Liang, et al. "Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and-9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma." Molecular Medicine Reports. (2015).  WB ;  
[IF=1.55] Hou, Yan, et al. "miR?215 functions as a tumor suppressor and directly targets ZEB2 in human non?small cell lung cancer." Oncology Letters.  WB ;  Human.  
[IF=1.55] Qi, Zhonghua, et al. "Naringin ameliorates cognitive deficits via oxidative stress, proinflammatory factors and the PPARγ signaling pathway in a type 2 diabetic rat model." Molecular Medicine Reports.  WB ;  
[IF=1.55] Chang, Liang, et al. "Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and-9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma. Corrigendum in/mmr/12/5/7815." Molecular medicine reports 12.5 (2015): 6702-6710.  WB ;  Human.  
[IF=1.55] Cheng, Yunpeng, et al. "Effect of oxidized low-density lipoprotein on the expression of the prorenin receptor in human aortic smooth muscle cells."Molecular medicine reports 11.6 (2015): 4341-4344.  WB ;  Human.  
[IF=1.55] Zhang, Zhongti, et al. "Jak3 is involved in CCR7-dependent migration and invasion in metastatic squamous cell carcinoma of the head and neck." Oncology Letters 13.5 (2017): 3191-3197.  WB ;  Human.  
[IF=1.55] Lv, Liang, et al. "Invasive Pituitary Adenoma-Derived Tumor-Associated Fibroblasts Promote Tumor Progression both In Vitro and In Vivo." Experimental and Clinical Endocrinology & Diabetes (2017).  WB ;  Rat.  
[IF=1.52] Zhu et al. Expression of serotonin receptors in the colonic tissue of chronic diarrhea rats. (2016) Saudi.J.Gastroentero. 22:234-9  WB ;  Rat.  
[IF=1.52] Liang Q et al. Evaluation of a modified rat model for functional dyspepsia.Saudi J Gastroenterol. 2018 Jul-Aug;24(4):228-235.  WB ;  Rat.  
[IF=1.496] Guo et al. Insulin-like growth factor-1 promotes osteogenic differentiation and collagen I alpha 2 synthesis via induction of mRNA-binding protein LARP6 expression. (2017) Dev.Growth.Differ. 59:94-103  WB ;  Mouse.  
[IF=1.482] Ji and Jiang Effect of shRNA-mediated inhibition of Nanog gene expression on the behavior of human gastric cancer cells. (2013) Oncol.Let. 6:367-374  WB ;  Human.  
[IF=1.48] Yan, Weihong, et al. "The effect of miR-146a on STAT1 expression and apoptosis in acute lymphoblastic leukemia Jurkat cells." Oncology Letters.  WB ;  Human.  
[IF=1.466] Li G et al. Effect of lncRNA ANRIL knockdown on proliferation and cisplatin chemoresistance of osteosarcoma cells in vitro. Pathol Res Pract. 2019 Jan 30. pii: S0344-0338(18)31655-8.  WB ;  Human.  
[IF=1.44] Zhou F et al.Salidroside protected against MPP+‐induced Parkinson's disease in PC12 cells by inhibiting inflammation, oxidative stress and cell apoptosis.(2018) Biotechnol Appl Biochem.  WB ;  Rat .  
[IF=1.438] Jiang?JY et al. Effects of estradiol and progesterone on secretion of epidermal growth factor and insulin-like growth factor-1 in cultured yak endometrial epithelial cells. Tissue Cell. 2018 Jun;52:28-34.  WB ;  Yak.  
[IF=1.422] Ran M et al. miR-26a suppresses autophagy in swine Sertoli cells by targeting ULK2.Reprod Domest Anim. 2018 Aug;53(4):864-871.   WB ;  Shaziling boar.  
[IF=1.42] Karaboga, ?hsan, Selim Demirtas, and Turan Karaca. "Investigation of the relationship between the Th17/IL-23 pathway and innate-adaptive immune system in TNBS-induced colitis in rats." Iranian Journal of Basic Medical Sciences 20.8 (2017): 870-879.  WB ;  Rat.  
[IF=1.41] Wu and Huang Synergistic enhancement of matrix metalloproteinase-9 expression and pro-inflammatory cytokines by influenza virus infection and oxidized-LDL treatment in human endothelial cells. (2017) Exp.Ther.Med. 14:4579-4585  WB ;  human.  
[IF=1.41] Song et al. Effects of HSYA on the proliferation and apoptosis of MSCs exposed to hypoxic and serum deprivation conditions. (2018) Exp.Ther.Med. 15:5251-5260  WB ;  Rat.  
[IF=1.396] Su N et al. Wnt/β-catenin deficiency inhibits multiple myeloma cell growth via AMPK/mTOR signaling. Int J Clin Exp Med. 2018;11(6):5657-5665.  WB ;  Human.  
[IF=1.39] Chen et al. Wnt4 overexpression promotes thymoma development through a JNK-mediated planar cell polarity-like pathway. (2018) Oncol.Lett. 15:83-90  WB ;  Human.  
[IF=1.39] Cao et al. MicroRNA-100 suppresses human gastric cancer cell proliferation by targeting CXCR7. (2018) Oncol.Lett. 15:453-458  WB ;  Human.  
[IF=1.39] Chen, Yuan, et al. "Wnt4 overexpression promotes thymoma development through a JNK?mediated planar cell polarity?like pathway." Oncology Letters.  WB ;  Human.  
[IF=1.39] Chang et al. MicroRNA-133b inhibits cell migration and invasion by targeting matrix metalloproteinase 14 in glioblastoma. (2015) Oncol.Let. 10:2781-2786  WB ;  Human.  
[IF=1.39] Chang et al. MicroRNA-133b inhibits cell migration and invasion by targeting matrix metalloproteinase 14 in glioblastoma. (2015) Oncol.Let. 10:2781-2786  WB ;  Human.  
[IF=1.38] Huang, Chen, et al. "Expression, purification, and functional characterization of recombinant PTD-SARA." Acta biochimica et biophysica Sinica 43.2 (2011): 110-117.  WB ;  
[IF=1.37] Zhu et al. Expression of serotonin receptors in the colonic tissue of chronic diarrhea rats. (2016) Saudi.J.Gastroentero. 22:234-9  WB ;  Rat.  
[IF=1.344] Gu et al. Angiopoietin-1 and Angiopoietin-2 Expression Imbalance Influence in Early Period After Subarachnoid Hemorrhage. (2016) Int.Neurourol.. 20:288-295  WB ;  Rat.  
[IF=1.311] Nie Y et al. KH-type splicing regulatory protein is regulated by nuclear factor-κB signaling to mediate innate immunity in Caco-2 cells infected by Salmonella enteritidis.Folia Microbiol (Praha). 2018 Nov;63(6):669-676.   WB ;  Human.  
[IF=1.31] Wang, Chunqiang, Wei Ma, and Yuhong Su. "NF-??B Pathway Contributes to Cadmium-Induced Apoptosis of Porcine Granulosa Cells."Biological trace element research (2013): 1-8.c  WB ;  Pig.  
[IF=1.28] Wu, Xue-Mei, et al. "Inhibition of connexin 36 decreases seizure activity in the Kainic acid-induced rat model of epilepsy." Int J Clin Exp Med 9.2 (2016): 2277-2284.  WB ;  Rat.  
[IF=1.28] Li, Yunlun, et al. "Mechanism of the protective effects of the combined treatment with rhynchophylla total alkaloids and sinapine thiocyanate against a prothrombotic state caused by vascular endothelial cell inflammatory damage." Experimental and Therapeutic Medicine.  WB ;  Mouse.  
[IF=1.28] Zhong et al. Inhibition of proliferation of human lung cancer cells by green tea catechins is mediated by upregulation of let-7. (2012) Exp.Ther.Me. 4:267-272  WB ;  Human.  
[IF=1.28] Yang et al. Effect of saw palmetto extract on PI3K cell signaling transduction in human glioma. (2014) Exp.Ther.Me. 8:563-566  WB ;  Human.  
[IF=1.25] Zhao, Yu, and Shijun Wang. "Neural Stem Cell Transplantation Inhibits Apoptosis through Activation of MAPK/ERK Signaling Pathway in Cerebral Ischemia/Reperfusion Rats." International Journal of Clinical and Experimental Neurology 1.1 (2013): 5-11.  WB ;  Rat.  
[IF=1.22] Ma, Lili, et al. "Mori cortex prevents kidney damage through inhibiting expression of inflammatory factors in the glomerulus in streptozocin-induced diabetic rats." Iranian Journal of Basic Medical Sciences 20.6 (2017): 715-721.  WB ;  Rat.  
[IF=1.22] Ma et al. Mori cortex prevents kidney damage through inhibiting expression of inflammatory factors in the glomerulus in streptozocin-induced diabetic rats. (2017) Iran.J.Basic.Med.Sc. 20:715-721  WB ;  Rat.  
[IF=1.189] Cai YH et al. Riboflavin/ultraviolet A-induced collagen cross-linking in rabbit corneal scar. Int J Ophthalmol. 2019 Jan 18;12(1):46-50.   WB ;  Rabbit.  
[IF=1.189] Jiang JQ et al. Inhibition of LOX-1 alleviates the proinflammatory effects of high-mobility group box 1 in Aspergillus fumigatus keratitis. Int J Ophthalmol. 2019 Jun 18;12(6):898-903.   WB ;  Mouse.  
[IF=1.166] Liu M et al. Boxb mediate BALB/c mice corneal inflammation through a TLR4/MyD88-dependent signaling pathway in Aspergillus fumigatus keratitis.Int J Ophthalmol. 2018 Apr 18;11(4):548-552.  WB ;  Mouse.  
[IF=1.14] Wang, J., et al. "Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway." Brazilian Journal of Medical and Biological Research (2014): 000-000.  WB ;  Mouse.  
[IF=1.1] Zhou, Jing, et al. "Effects of low-dose hydroxychloroquine on expression of phosphorylated Akt and p53 proteins and cardiomyocyte apoptosis in peri-infarct myocardium in rats."?Experimental & Clinical Cardiology?18.2 (2013): e95.  WB ;  Rat.  
[IF=1.09] Zhao, Zhilong, et al. "Expression of natriuretic peptide receptor-A in esophageal squamous cell carcinomas and the relationship with tumor invasion and migration." World Journal of Surgical Oncology 12.1 (2014): 154.  WB ;  Human.  
[IF=1.07] Liu, Cui-Zhen, et al. "HBSP attenuates lipopolysaccharide-induced inflammatory response in human renal proximal tubular epithelial cells by induction of Nrf2 via PI3K/Akt pathway." Int J Clin Exp Med 10.1 (2017): 587-597.  WB ;  Human.  
[IF=1] Yang, Huihai, et al. "Anticancer activity in vitro and biological safety evaluation in vivo of Sika deer antler protein." Journal of Food Biochemistry(2017).  WB ;  Other Species.  
[IF=1] Gou, Xun, et al. "Effect of social interaction on learning and memory of morphine withdrawal mice." Int J Clin Exp Med10.10 (2017): 14477-14485.  WB ;  Mouse.  
[IF=.9] Zhang, Xiao-ling, et al. "Vascular endothelial growth factor up-regulates the expression of intracellular adhesion molecule-1 in retinal endothelial cells via reactive oxygen species, but not nitric oxide." Chinese Medical Journal (English Edition) 122.3 (2009): 338.  WB ;  Bovine.  
[IF=.9] Suzuki, Tomoyuki, et al. "Atrial natriuretic peptide induces peroxisome proliferator activated receptor γ during cardiac ischemia–reperfusion in swine heart." General Thoracic and Cardiovascular Surgery (2016): 1-11.  WB ;  Pig.  
[IF=.84] Liu, Xiao-Lan, et al. "Increased expression of Dock180 protein in the noninfarcted myocardium in rats." Journal of the Chinese Medical Association 76.3 (2013): 164-168.  WB ;  Rat.  
[IF=.78] Ma, X., et al. "Molecular cloning and expression vector construction of bovine TRIM28 Genet. Mol. Res. 15 (2)." Genet. Mol. Res 15: 2.  WB ;  Bovine.  
[IF=.73] Asada, Dai, Toshiyuki Itoi, and Kenji Hamaoka. "The tolerance to ischemia reperfusion injury in a congenital heart disease model." Pediatrics International (2016)  WB ;  Rat.  
[IF=.63] Mu, Yang, et al. "Up-regulation of phosphorylated ATM/ATR substrate/Akt expression by phenylephrine in peri-infarct myocardium in rats." Acta Cardiol Sin 27.3 (2011): 182-8.  WB ;  Rat.  
[IF=.6] Yin, Zhihong, et al. "Identification of differentially expressed Gnαs and Gnα11 in sheep (Ovis aries) skins associated with white and black coat colors." Acta histochemica (2016).  WB ;  Sheep.  
[IF=.57] Shi, Hua-Li, et al. "Effect of polygonimitin C on bone formation and resorption in human osteoblast-like MG63 cells." Tropical Journal of Pharmaceutical Research 16.7 (2017): 1595-1600.  WB ;  Human.  
[IF=.437] Ma?X et al. Expression and characterization of a lysine rich protein in cow milk. Indian J. Anim. Res.,2019 53(7):874-879.  WB ;  Human.  
[IF=.34] Wang, Gui-Jun, et al. "Expression of tissue factor pathway inhibitor-2 in gastric stromal tumor and its clinical significance." Experimental and Therapeutic Medicine.  WB ;  Human.  
[IF=.181] Zhao R et al. IE86 Inhibits the apoptosis and promotes the cell proliferation of glioma cells via the hnRNP A2/B1-mediated alternative splicing of Bcl-x. Int J Clin Exp Pathol 2019;12(7):2775-2785  WB ;  Human.  
[IF=.181] Jiao M et al. Protective effect of hydrogen sulfide against neuronal apoptosis via inhibiting neuroinflammation in Parkinson rats. Int J Clin Exp Med 2019;12(5):4935-4941  WB ;  Rat.  
[IF=.13] Zhang, Z. J., et al. "Prospective experimental studies on the renal protective effect of ulinastatin after paraquat poisoning." World J Emerg Med 3.4 (2012): 299-304.  WB ;  Rat.  
[IF=0] Yin et al. Topical pimecrolimus inhibits high-dose UVB irradiation-induced epidermal Langerhans cell migration, via regulation of TNF-α and E-cadherin. (2014) Drug.Des.Devel.Ther. 8:1817-25  WB/FC ;  Human.  
[IF=0] Li et al. Morusin suppresses breast cancer cell growth in vitro and in vivo through C/EBPβ and PPARγ mediated lipoapoptosis. (2015) J.Exp.Clin.Cancer.Res. 34:137  WB ;  Human.  
[IF=0] Li et al. Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4(+)CD25(+) regulatory T cells. (2016) Neuropsychiatr.Dis.Treat. 12:883-96  WB ;  Rat.  
[IF=0] Wang et al. Time-dependent effects of late-onset dietary intake of salidroside on lifespan and age-related biomarkers of the annual fish Nothobranchius guentheri. (2018) Oncotarget. 9:14882-14894  WB ;  Fish.  
[IF=0] Sakaguchi et al. Bromodomain protein BRD4 inhibitor JQ1 regulates potential prognostic molecules in advanced renal cell carcinoma. (2018) Oncotarget. 9:23003-23017  WB ;  human.  
[IF=0] Zhu et al. Vγ9Vδ2 T cells inhibit immature dendritic cell transdifferentiation into osteoclasts through downregulation of RANK, c?Fos and ATP6V0D2. (2018) Int.J.Mol.Med. 42:2071-2079  WB ;  Human .  
[IF=0] Sondag, Gregory R. OSTEOACTIVIN AND CD44: A NOVEL INTERACTION REGULATING BONE CELL DIFFERENTIATION AND FUNCTION. Diss. Kent State University, 2015.  WB ;  Mouse.  
[IF=0] Xu, Jing, et al. "Construction of Conveniently Screening pLKO. 1-TRC Vector Tagged with TurboGFP." Applied Biochemistry and Biotechnology(2016): 1-11.  WB ;  Human.  
[IF=0] Li et al. Galangin Induces Autophagy via Deacetylation of LC3 by SIRT1 in HepG2 Cells. (2016) Sci.Re. 6:30496  WB ;  Human.  
[IF=0] Lai et al. PKCδ silencing alleviates saturated fatty acid induced ER stress by enhancing SERCA activity. (2017) Biosci.Re. 37   WB ;  Human.  
[IF=0] Zhang et al. Expression of Heat Shock Protein-27 (Hsp27) and P38MAPK in Esophageal Squamous Cell Carcinoma. (2017) Med.Sci.Moni. 23:5246-5253  WB ;  Human.  
[IF=0] Liu et al. PD-1/PD-L1 interaction up-regulates MDR1/P-gp expression in breast cancer cells via PI3K/AKT and MAPK/ERK pathways. (2017) Oncotarget. 8:99901-99912  WB ;  
[IF=0] Luan et al. Long non-coding RNA MIAT promotes breast cancer progression and functions as ceRNA to regulate DUSP7 expression by sponging miR-155-5p. (2017) Oncotarget. 8:76153-76164  WB ;  
[IF=0] Nie et al. The effect of depression on fracture healing and osteoblast differentiation in rats. (2018) Neuropsychiatr.Dis.Treat. 14:1705-1713  WB ;  Rat.  
[IF=0] Han B et al. 8-Cetylcoptisine, a new coptisine derivative, induces mitochondria-dependent apoptosis and G0/G1 cell cycle arrest in human A549 cells.(2018)Chem Biol Interact.;299:27-36.  WB ;  Mouse.  
[IF=0] Kaushal P et al. Ameliorative role of antioxidant supplementation on sodium-arsenite induced adverse effects on the developing rat cerebellum. Journal of Ayurveda and Integrative Medicine.2019  WB ;  Rat.  
[IF=0] Tang Y et al. Electroacupuncture?Mitigates?Hippocampal?Cognitive?Impairments?by?Reducing?BACE1Deposition?and?Activating?PKA?in?APP/PS1?Double?Transgenic?Mice. Neural Plast. 2019 May 15;2019:2823679.   WB ;  Rat.  
[IF=0] Zhang XD et al. MiR-26a promotes apoptosis of porcine granulosa cells by targeting the 3β-hydroxysteroid-Δ24-reductase gene. Asian-Australas J Anim Sci. 2019,July 1.  WB ;  Pig.  
[IF=0] Wang T et al. Picroside II protects SH‐SY5Y cells from autophagy and apoptosis following oxygen glucose deprivation/reoxygen injury by inhibting JNK signal pathway. The Anatomical Record.?2019,July 11.  WB ;  Human.  
[IF=0] Li T et al. Digital gene expression analyses of mammary glands from meat ewes naturally infected with clinical mastitis. R. Soc. open sci. 2019,6: 181604.  WB ;  Sheep.  
[IF=0] Liao XD et al. Effect of all-trans retinoic acid on casein and fatty acid synthesis in MAC-T cells. Asian-Australas J Anim Sci. 2019 Aug 23.   WB ;  bovine.  
[IF=0] Jin Y et al. TRIM21 mediates ubiquitination of Snail and modulates epithelial to mesenchymal transition in breast cancer cells. International Journal of Biological Macromolecules. 2018.  WB ;  Human.  
[IF=0] Wang M et al. Rhynchophylline attenuates allergic bronchial asthma by inhibiting transforming growth factor-β1-mediated Smad and mitogen-activated protein kinase signaling transductions in vivo and in vitro. Exp Ther Med.?2019 Jan;17(1):251-259.  WB ;  Mouse.  
[IF=4.255] Chen L et al. Lysophosphatidic acid decreased macrophage foam cell migration correlated with downregulation of fucosyltransferase 8 via HNF1α. Atherosclerosis. 2019 Sep 11;290:19-30.   WB ;  Mouse&Human.  
[IF=3.414] Li ZH et al. You-Gui-Yin improved the reproductive dysfunction of male rats with chronic kidney disease via regulating the HIF1α-STAT5 pathway. J Ethnopharmacol. 2020 Jan 10;246:112240.  WB ;  Rat.  
[IF=3.244] Zhou L et al. JLX001 Ameliorates Ischemia/Reperfusion Injury by Reducing Neuronal Apoptosis Via Downregulating JNK Signaling Pathway. Neuroscience 418 (2019) 189–204.  WB ;  Rat.  
[IF=2.302] Deng K et al. miR-27a is an important adipogenesis regulator associated with differential lipid accumulation between intramuscular and subcutaneous adipose tissues of sheep. Domestic Animal Endocrinology.2019Sep.  WB ;  Sheep.  
[IF=2.302] Li Q et al. All-trans retinoic acid regulates sheep primary myoblasts proliferation and differentiation in vitro. Domestic Animal Endocrinology,2019 106394.   WB ;  Sheep.  
[IF=2.299] Yang WR et al. Oxidative stress mediates heat-induced changes of tight junction proteins in porcine Sertoli cells via inhibiting CaMKKβ-AMPK pathway. Theriogenology. 2019 Sep 19;142:104-113.   WB ;  Piglet.  
[IF=1.376] Song MN et al. Effects of Actigen, a second-generation mannan rich fraction, in antibiotics_x0002_free diets on growth performance, intestinal barrier functions and inflammation in weaned piglets. Livestock Science 229 (2019) 4–12.  WB ;  Piglet.  
[IF=1.26] Qian ZK et al. Alisma orientalis (Sam.) juzep polysaccharide-regulated glucose-lipid metabolism in experimental rats and cell model of diabetes mellitus with regulation of miR-126. Pharmacognosy Magazine,2019 15(65): 652-658.  WB ;  Human.  
[IF=0] Xu LR et al. Inhibition of the Nrf2-TrxR Axis Sensitizes the Drug-Resistant Chronic Myelogenous Leukemia Cell Line K562/G01 to Imatinib Treatments. ChemRxiv.2019Sep.  WB ;  Human.  
[IF=0] Xu YY et al. L-type Calcium Channels are Involved in Iron-induced Neurotoxicity in Primary Cultured Ventral Mesencephalon Neurons of Rats. Neurosci Bull. 2019 Sep 3.   WB ;  Rat.  
[IF=2.515] Li T et al. Digital gene expression analyses of mammary glands from meat ewes naturally infected with clinical mastitis.R Soc Open Sci. 2019 Jul 3;6(7):181604.   WB ;  Sheep.  
[IF=3.331] Wang X et al. Characterization of GLOD4 in Leydig Cells of Tibetan Sheep During Different Stages of Maturity.Genes (Basel). 2019 Oct 12;10(10). pii: E796.  WB ;  Sheep.  
產品類型 內參抗體 
研究領域 腫瘤  細胞生物  信號轉導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Chicken, Dog, Rabbit, Sheep, Bee, Fish, Guinea Pig, Hamster, Cat, mt,op
產品應用 WB=1:5000-20000 ELISA=1:5000-20000 IHC-P=1:500-1000 Flow-Cyt=1μg/Test ICC=1:100 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Synthetic MAP peptide derived from human beta-Actin:1-200/375 
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
產品介紹 Loading Control
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008].

Function:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Subunit:
Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of the MLL5-L complex, at least composed of MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2.

Subcellular Location:
Cytoplasm. cytoskeleton.

Tissue Specificity:
Ubiquitously expressed in all eukaryotic cells.

Post-translational modifications:
ISGylated.
Oxidation of Met-44 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. Methionine sulfoxide is produced stereospecifically, but it is not known whether the (S)-S-oxide or the (R)-S-oxide is produced.

DISEASE:
Defects in ACTA1 are the cause of nemaline myopathy type 3 (NEM3) [MIM:161800]. A form of nemaline myopathy. Nemaline myopathies are muscular disorders characterized by muscle weakness of varying severity and onset, and abnormal thread-or rod-like structures in muscle fibers on histologic examination. The phenotype at histological level is variable. Some patients present areas devoid of oxidative activity containg (cores) within myofibers. Core lesions are unstructured and poorly circumscribed.
Defects in ACTA1 are a cause of myopathy congenital with excess of thin myofilaments (MPCETM) [MIM:161800]. A congenital muscular disorder characterized at histological level by areas of sarcoplasm devoid of normal myofibrils and mitochondria, and replaced with dense masses of thin filaments. Central cores, rods, ragged red fibers, and necrosis are absent.

Similarity:
Belongs to the actin family.

SWISS:
P60709

Gene ID:
60

Database links:

Entrez Gene: 396526 Chicken

Entrez Gene: 60 Human

Entrez Gene: 11461 Mouse

Entrez Gene: 100009272 Rabbit

Entrez Gene: 81822 Rat

Omim: 102630 Human

SwissProt: P60706 Chicken

SwissProt: P60712 Cow

SwissProt: P60708 Horse

SwissProt: P60709 Human

SwissProt: P60710 Mouse

SwissProt: P29751 Rabbit

SwissProt: P60711 Rat

SwissProt: P60713 Sheep

Unigene: 520640 Human

Unigene: 708120 Human

Unigene: 727576 Human

Unigene: 328431 Mouse

Unigene: 391967 Mouse

Unigene: 94978 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

內參抗體
β-Actin是橫紋肌肌纖維中的一種主要蛋白質成分,也是肌肉細絲及細胞骨架微絲的主要成分。具有收縮功能,分布廣泛,具有高度保守性,在細胞中的表達相對穩定,因此常被用作校正系統的內參。β-Actin分子量為42 kDa,
此抗體主要用于標記平滑肌及其來源的腫瘤。
我公司開發的β-Actin抗體已被國內外廣大科研工作者使用,被稱謂:質量信得過產品.
產品圖片
Sample:
Lung (Mouse) Lysate at 40 ug
Uterus (Mouse) Lysate at 40 ug
Small intestine (Mouse) Lysate at 40 ug
Primary: Anti- beta-Actin (bs-0061R) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
A549 Cell (Human) Lysate at 30 ug
Primary: Lane1: Anti-beta-Actin (bs-0061R) at 1/500 dilution
Lane2: Anti-beta-Actin (bs-0061R) at 1/1000 dilution
Lane3: Anti-beta-Actin (bs-0061R) at 1/2000 dilution
Lane4: Anti-beta-Actin (bs-0061R) at 1/4000 dilution
Lane5: Anti-beta-Actin (bs-0061R) at 1/5000 dilution
Lane6: Anti-beta-Actin (bs-0061R) at 1/8000 dilution
Lane7: Anti-beta-Actin (bs-0061R) at 1/10000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
A549 Cell (Human) Lysate at 30 ug
Primary: Lane1: Anti-beta-Actin (bs-0061R) at 1/500 dilution
Lane2: Anti-beta-Actin (bs-0061R) at 1/1000 dilution
Lane3: Anti-beta-Actin (bs-0061R) at 1/2000 dilution
Lane4: Anti-beta-Actin (bs-0061R) at 1/4000 dilution
Lane5: Anti-beta-Actin (bs-0061R) at 1/5000 dilution
Lane6: Anti-beta-Actin (bs-0061R) at 1/8000 dilution
Lane7: Anti-beta-Actin (bs-0061R) at 1/10000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
Lane1: 293T Cell Lysate at 25 ug
Lane2: A549 Cell Lysate at 25 ug
Lane3: A431 Cell Lysate at 25 ug
Primary: Anti- beta-Actin (bs-0061R) at 1/1000 and 1/5000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42kD
Observed band size: 42 kD
Sample: Lung lysate at 30ug;
Primary: Anti-beta-actin (bs-0061R) at 1:1000 dilution
Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bse-0295G) at 1:3000 dilution
Predicted band size : 42kD
Observed band size : 42kD
Sample:
HL60 (Human) Cell Lysate at 40 ug
HUVEC (Human) Cell Lysate at 40 ug
Spinal cord (Rat) Lysate at 40 ug
Rectum (Rat) Lysate at 40 ug
Placenta (Rat) Lysate at 40 ug
Lymph node (Rat) Lysate at 40 ug
Lung (Rat) Lysate at 40 ug
Spleen (Rat) Lysate at 40 ug
JAR (Human) Cell Lysate at 40 ug
293T (Human) Cell Lysate at 40 ug
Jurkat (Human) Cell Lysate at 40 ug
TM4 (Human) Cell Lysate at 40 ug
Primary: Anti-beta-Actin (bs-0061R) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
A549 (Human) Cell Lysate at 40 ug
Raw264.7 (Mouse) Cell Lysate at 40 ug
SH-SY5Y (Human) Cell Lysate at 40 ug
MKN45 (Human) Cell Lysate at 40 ug
CHO (Human) Cell Lysate at 40 ug
Panc-1 (Human) Cell Lysate at 40 ug
4T1 (Human) Cell Lysate at 40 ug
ASPC-1 (Human) Cell Lysate at 40 ug
H9C2 (Rat) Cell Lysate at 40 ug
Brl-3a (Rat) Cell Lysate at 40 ug
TT (Human) Cell Lysate at 40 ug
TEV-1 (Human) Cell Lysate at 40 ug
EC9706 (Human) Cell Lysate at 40 ug
Primary: Anti-beta-Actin (bs-0061R) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
Embryo Cerebrum (Mouse) Lysate at 40 ug
Du145 (Human) Lysate at 40 ug
SW480 (Human) Cell Lysate at 40 ug
U87MG (Human) Lysate at 40 ug
U251 (Human) Lysate at 40 ug
A673 (Human) Lysate at 40 ug
Lovo (Human) Lysate at 40 ug
293FT (Human) Lysate at 40 ug
JEG-3 (Human) Lysate at 40 ug
RSC96 (Rat) Cell Lysate at 40 ug
MCF-7 (Human) Cell Lysate at 40 ug
HepG2 (Human) Lysate at 40 ug
A431 (Human) Lysate at 40 ug
Primary: Anti-beta-Actin (bs-0061R) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
Thymus (Mouse) Lysate at 40 ug
Urinary bladder (Mouse) Lysate at 40 ug
Uterus (Mouse) Cell Lysate at 40 ug
Aorta (Mouse) Lysate at 40 ug
olfactory bulb (Mouse) Lysate at 40 ug
Cerebellum (Mouse) Lysate at 40 ug
Adrenal gland (Mouse) Lysate at 40 ug
Ovary (Mouse) Lysate at 40 ug
Ear (Mouse) Lysate at 40 ug
U2os (Human) Cell Lysate at 40 ug
ASPC-1 (Human) Cell Lysate at 40 ug
Vas deferens (Mouse) Lysate at 40 ug
trachea (Mouse) Lysate at 40 ug
Primary: Anti-beta-Actin (bs-0061R) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
Lung (Mouse) Lysate at 40 ug
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-beta-Actin (Loading Control) (bs-0061R) at 1/2000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 42 kD
Tissue/cell: human cervical carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Beta-actin Polyclonal Antibody, Unconjugated(bs-0061R) 1:1500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: Hela cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (beta-Actin) polyclonal Antibody, Unconjugated (bs-0061R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG-FITC antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
MCF7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (beta-Actin) polyclonal Antibody, Unconjugated (bs-0061R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
MCF7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (beta-Actin) polyclonal Antibody, Unconjugated (bs-0061R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.
Blank control:Mouse spleen.
Primary Antibody (green line): Rabbit Anti-beta-Actin (Loading Control) antibody (bs-0061R)
Dilution: 2μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG .
Secondary Antibody : Goat anti-rabbit IgG-AF647
Dilution: 1μg /test.
Protocol
The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 90% ice-cold methanol for 20 min at-20℃. The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
Blank control: RSC96(blue).
Primary Antibody: Rabbit Anti-beta-Actin /FITC Conjugated antibody (bs-0061R/FITC), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG/FITC(orange) ,used under the same conditions.
Protocol
The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice. The cells were washed twice with 1 X PBS. The cells were incubated in 1 X PBS containing 0.5% BSA + 1 0% goat serum (15 min) to block non-specific protein-protein interactions followed by the incubated with antibody (bs-0061R/FITC, 1μg /1x10^6 cells) for 30 min on ice. Acquisition of 20,000 events was performed.
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